Naples is a city in Italy; it is the capital of the region of Campania and of the province of Naples. Known for its rich history, art, culture, architecture, music, and gastronomy, Naples has played an important role in the Italian peninsula and beyond for much of its existence, which began more than 2,800 years ago. Situated on the west coast of Italy by the Gulf of Naples, the city is located halfway between two volcanic areas, Mount Vesuvius and the Phlegraean Fields. Naples has the fourth-largest urban economy in Italy, after Milan, Rome and Turin. It is the world's 103rd-richest city by purchasing power, with an estimated 2011 GDP of US$83.6 billion. The port of Naples is one of the most important in Europe, and has the world's second-highest level of passenger flow, after the port of Hong Kong. The city has long been a major cultural centre with a global sphere of influence, particularly during the Renaissance and Enlightenment eras. In the immediate vicinity of Naples are numerous culturally and historically significant sites, including the Palace of Caserta and the Roman ruins ofPompeii and Herculaneum. Culinarily, it is synonymous with pizza, which originated in the city.

The capital of Portugal, Lisbon (Portuguese: Lisboa) has experienced a renaissance in recent years, with a contemporary culture that is alive and thriving and making its mark in today's Europe. Perched on the edge of the Atlantic Ocean, Lisbon is one of the rare Western European cities that faces the ocean and uses water as an element that defines the city. Lisbon enchants travellers with its white-bleached limestone buildings, intimate alleyways, and an easy-going charm that makes it a popular year-round destination.

Barcelona – Spain's enchanting capital, second largest and most populous city. It is a huge city that vibrates with life, and there’s certainly not another city in the country to touch it for its sheer style, looks or energy. It is one of the world's leading tourist, economic, trade fair and cultural centers, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. Barcelona is home to masterpieces of many great architects – the most famous of which is Antoni Gaudí. 

Cartagena is a Spanish city and a majornaval station located in the Region of Murcia, by the Mediterranean coast, south-eastern Spain. The metropolitan area of Cartagena, known as Campo de Cartagena, has a population of 409,586 inhabitants. Cartagena has been inhabited for over two millennia, being founded around 227 BC by the Carthaginian Hasdrubal the Fair as Qart Hadasht, the same name as the original city of Carthage. Much of the historical weight of Cartagena in the past goes to its coveted defensive port, one of the most important in the western Mediterranean. As far back as the 16th century it was one of the most important naval ports in Spain, together with Ferrol in the North. It is still an important naval seaport, the main military haven of Spain, and is home to a large naval shipyard. The confluence of civilizations as well as its strategic harbour, together with the rise of the local mining industry is manifested by a unique artistic heritage, with a number of landmarks such as the Roman Theatre, the second largest of the Iberian Peninsulaafter the one in Mérida, an abundance of Phoenician, Roman, Byzantine and Moorish remains, and a plethora of Art Nouveaubuildings, a result of the bourgeoisie from the early 20th century. Cartagena is now established as a major cruise ship destination in the Mediterranean and an emerging cultural focus. It is the first of a number of cities that eventually have been named Cartagena, most notably Cartagena de Indias (Cartagena of the Indies) in Colombia.

Civitavecchia is a town and comune of the Metropolitan City of Rome in the central Italian region of Lazio. A sea port on the Tyrrhenian Sea, the name ''Civitavecchia'' means "ancient town". The modern city was built over a pre-existing Etruscan settlement. The massive Forte Michelangelo was first commissioned from Donato Bramante by Pope Julius II, to defend the port of Rome. The upper part of the "maschio" tower, however, was designed by Michelangelo, whose name is generally applied to the fortress. North of the city at Ficoncella are the Terme Taurine baths frequented by Romans and still popular with the Civitavecchiesi. The modern name stems from the common fig plants among the various pools. And also next to the town is the location of the cruise ship docks. All major cruise lines start and end their cruises at this location, and others stop for shore excursion days that allow guests to see Rome and Vatican sights, which are ninety minutes away.